Sunday, August 10, 2014

Ebola - Africa's Bloody Disease

The Ebola virus was first associated with an outbreak of 318 cases of a hemorrhagic disease in Zaire. Of the 318 cases, 280 of them died—and died quickly. That same year, 1976, 284 people in Sudan also became infected with the virus and 156 died.

The viruses that cause Ebola and Marburg are similar, infecting both monkeys and people. The outbreaks of these diseases are often self-contained, however, because they kill their hosts so quickly that they rapidly run out of people to infect.

The Zaire strain of Ebola virus has a mortality rate of 88 percent, which is higher than either the Sudan strain of Ebola or the Marburg virus.

Antigen Alert
A closely related virus, called Reston, was isolated from animals in the Philippines, indicating that these diseases are not completely confined to Africa. So far, Reston has not been found to cause disease in people.

The Ebola virus spreads through the blood, multiplying in many organs. It causes severe damage to the liver, lymphatic system, kidneys, ovaries, and testes. Platelets and linings of arteries are severely damaged, which results in profuse bleeding. Mucosal surfaces of the stomach, heart membrane, and vagina are also affected. Internal bleeding results in shock and acute respiratory distress, leading to death.

Ebola's Frightening Symptoms

Once a patient is infected with Ebola, the incubation period is 4 to 16 days. The onset of disease is sudden, with fever, chills, headache, anorexia, and muscle pain. As the disease progresses, nausea, vomiting, sore throat, stomach pain, and diarrhea are common. Most patients develop severe hemorrhages, usually between days five and seven. Bleeding occurs from multiple sites, including the digestive tract, lungs, and gums. Death occurs within 7 to 16 days. 

Infectious Knowledge

The Ebola virus was named after the Ebola River, in the Congo. The disease has occurred in Congo, Sudan, the Ivory Coast, and Uganda. There has never been a case in the United States.

Potent Fact  

Some people recover from Ebola. No one fully understands why.

How Ebola Is Spread

Epidemics result from person-to-person contact within communities, families, and hospitals, or from inadvertent laboratory exposures. The means of infection and the natural ecology of these viruses are largely unknown, although an association with monkeys and/or bats has been suggested.

Read more: Rare and Deadly Diseases: Ebola: Africa's Bloody Disease |